Online submission +


Online submission +

Volume 44 - Novembro 2022

DOI: s-0042-1757957

Adverse Events Related to COVID-19 Vaccines in Pregnant Women: Correspondence

Pathum Sookaromdee, Viroj Wiwanitkit

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Dear Editor,


We would like to share ideas on the publication “Adverse Events Related to COVID-19 Vaccines Reported in Pregnant Women in Brazil.”1 According to Kobayashi et al.,1 ten deaths were identified, one of which was thought to be causally related to the vaccine, and the other nine maternal deaths had causality C, that is, no causal relationship with the vaccine, and the majority were due to complications inherent in pregnancy, such as pregnancy-specific hypertensive disorder (PSHD) in four cases, and COVID-19 in three.1 The problem of the efficacy and safety of the COVID-19 vaccine for pregnant women is intriguing, and evidence from real-world situations are needed.2 Aside from death, there are further concerns about the safety of the COVID-19 vaccine for pregnant women, including the induction of abortion.3


We are all concerned that, despite its benefits, the COVID-19 vaccine may be harmful. It is difficult to determine the exact source of the clinical issue in this case due to a lack of information on the health and immunological status of vaccination recipients prior to inoculation. People may reject vaccines and lose faith in them if they are given contradicting information. A clinical comorbidity may be at the basis of the problem.4,5 The assessment of potential detrimental outcomes is now too early due to incomplete documentation of a person's health or immune condition prior to immunization.

1 Kobayashi CD, Porto VBG, da Nóbrega MEB, Cabral CM, Barros TD, Martins CMR. Adverse events related to COVID-19 vaccines reported in pregnant women in Brazil. Rev Bras Ginecol Obstet. 2022;•••:-

2 Joob B, Wiwanitkit V. Vaccine for Covid-19 and pregnant women. Rev Bras Ginecol Obstet. 2021;43(06):490-491

3 Sookaromdee P, Wiwanitkit V. Magnitude of abortion after COVID-19 vaccination: how about rate?. Erciyes Med J. 2022;44(02):244-244

4 Kebayoon A, Wiwanitkit V. Dengue after COVID-19 vaccination: possible and might be missed. Clin Appl Thromb Hemost. 2021;27:-

5 Sookaromdee P, Wiwanitkit V. Severe immune thrombocytopenia following COVID-19 vaccination. Am J Emerg Med. 2022;58:337-337